Pregnant women are forbidden to use antibiotics (especially the latest generation), as they have a negative impact on the development of the fetus. The most dangerous stage is the first half of pregnancy. For example, scientists have determined that if a mother was treated during pregnancy with two courses of antibiotics, then there is a…
Read MoreInside penicillins should be taken with a large volume of liquid (water, mineral water without gas). Ampicillin and oxacillin should be taken 1 hour before meals or 2 hours after meals, phenoxymethylpenicillin, amoxicillin and amoxicillin (clavulanate) – regardless of food intake.It is necessary to strictly observe the regimen prescribed by the doctor during the entire…
Read MorePenicillins should never be mixed in the same syringe with aminoglycosides because of their physical and chemical incompatibility. When ampicillin is combined with allopurinol, the risk of ampicillin rash increases dramatically. The administration of high doses of benzylpenicillin in combination with potassium preparations determines an increased risk of hyperkalemia. Extreme caution should be exercised when…
Read MoreBenzylpenicillin, carboxypenicillins and ureidopenicillins largely lose their properties when taken orally under the action of hydrochloric acid of gastric juice, for this reason they are administered only intramuscularly. Phenoxymethylpenicillin, oxacillin and aminopenicillins are more stable in an acidic environment, and therefore can be administered orally. A very high degree of absorption in the gastrointestinal tract…
Read MoreAllergic reactions: urticaria, rash, Quincke’s edema, fever, eosinophilia, bronchospasm, anaphylactic shock (more often when using benzylpenicillin). Measures to help with the development of anaphylactic shock: ensuring the airway patency, oxygen cushion, adrenaline, prednisone. From the Central nervous system: headache, tremors, convulsions (more often in children and in patients with renal insufficiency when using carbenicillin or…
Read MoreIncreasing the resistance of microorganisms to antibiotics is a global issue for public health organizations. The increase in resistance is particularly important for Pediatrics due to the frequent use of antibiotics for the treatment of common childhood infectious diseases in outpatient settings and severe infections in hospitals. For example, in various regions of the world,…
Read MoreAllergy. It is cross-linked to all antimicrobial drugs of the penicillin group. This means that if you are once allergic to a penicillin-type antibiotic, for example, ampicillin, it is also dangerous to use any other antibiotic from the penicillin group. Some patients with an allergic reaction to cephalosporins may allergies to penicillins may also occur.…
Read MoreNatural penicillins. Diseases that are treated primarily with penicillin antibiotics include tonsillopharyngitis, scarlet fever, erysipelas, community-acquired pneumonia, meningitis, sepsis, meningococcal infections, syphilis, leptospirosis, tick-borne borreliosis, gas gangrene, and actinomycosis. There are antibiotics that need to be taken several times a day, and there are those that are taken once a month. They have a prolonged…
Read MoreThe group of antibiotics under the General name “penicillins” includes the following drugs: amoxicillin, ampicillin, ampicillin with sulbactam, benzylpenicillin, cloxacillin, coamoxylav (amoxicillin with clavualanic acid), Flucloxacillin, methicillin, oxacillin, phenoxymethylpenicillin. Cephalosporins: cefaclor, cefadroxil, cefixime, cefoperazone, Cefotaxime, cefoxitin, cefpirome, cefsulodin, ceftazidime, ceftizoxime, Ceftriaxone, cefuroxime, cephalexin, cephalothin, of cefamandol, Cefazolin, cefradine. Penicillins and cephalosporins together with the antibiotics…
Read MoreAntibiotics are substances that selectively suppress the vital activity of microorganisms. “Selective influence” refers to the activity exclusively in the relationship of microorganisms while preserving the viability of host cells and the impact not on all, but only on certain genera and types of microorganisms. For example, fusidic acid has a high activity against staphylococci,…
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