ANTIBIOTICS APPROVED FOR USE DURING PREGNANCY

There are no contraindications for penicillin and cephalosporin. Penicillins act against strains of Gram-positive streptococci, staphylococci, enterococci and meningococci. Ampicillin and amoxicillin, in addition, have an effect against gram-negative bacteria. Cephalosporins are also effective against Gram-positive cocci and are more effective than penicillin against Gram-negative pathogens. Both groups of antibiotics can be administered throughout pregnancy.…

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INTERACTION OF PENICILLINS WITH OTHER DRUGS

Penicillins should never be mixed in the same syringe with aminoglycosides because of their physical and chemical incompatibility. When ampicillin is combined with allopurinol, the risk of ampicillin rash increases dramatically. The administration of high doses of benzylpenicillin in combination with potassium preparations determines an increased risk of hyperkalemia. Extreme caution should be exercised when…

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What HAPPENS to antibiotics AFTER THEY ENTER the body?

Benzylpenicillin, carboxypenicillins and ureidopenicillins largely lose their properties when taken orally under the action of hydrochloric acid of gastric juice, for this reason they are administered only intramuscularly. Phenoxymethylpenicillin, oxacillin and aminopenicillins are more stable in an acidic environment, and therefore can be administered orally. A very high degree of absorption in the gastrointestinal tract…

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LIST OF POSSIBLE UNDESIRABLE EFFECTS OF PENICILLIN ANTIBIOTICS

Allergic reactions: urticaria, rash, Quincke’s edema, fever, eosinophilia, bronchospasm, anaphylactic shock (more often when using benzylpenicillin). Measures to help with the development of anaphylactic shock: ensuring the airway patency, oxygen cushion, adrenaline, prednisone. From the Central nervous system: headache, tremors, convulsions (more often in children and in patients with renal insufficiency when using carbenicillin or…

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WHEN ANTIBIOTICS ARE PRESCRIBED

Natural penicillins. Diseases that are treated primarily with penicillin antibiotics include tonsillopharyngitis, scarlet fever, erysipelas, community-acquired pneumonia, meningitis, sepsis, meningococcal infections, syphilis, leptospirosis, tick-borne borreliosis, gas gangrene, and actinomycosis. There are antibiotics that need to be taken several times a day, and there are those that are taken once a month. They have a prolonged…

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